Endocrine Abstracts

Androgen stimulation triggers rapid activation of signaling pathways in target cells. The initial event is a rapid interaction of classical androgen receptor (AR) with Src. Activation of these pathways fosters cell cycle, prevents apoptosis and leads to cytoskeleton changes in reproductive as well as non-reproductive cells. The role of Src activation in the androgen proliferative action has been recently corroborated by findings showing that specific interference in Src/AR ass...